PROSITE entry PS50258
View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission
General information about the entry
Entry name [info] | LNR |
Accession [info] | PS50258 |
Entry type [info] | MATRIX |
Date [info] |
01-JAN-2006 CREATED;
01-OCT-2013 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC50258 |
Associated ProRule [info] | PRU00525 |
Name and characterization of the entry
Description [info] | LNR (Lin-12/Notch) repeat profile. |
Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=42; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=42; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3577006; R2=0.0056736; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=1700; N_SCORE=12.0; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=1083; N_SCORE=8.5; MODE=1; TEXT='RR'; /DEFAULT: M0=-20; D=-80; I=-80; B1=-200; E1=-200; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='C'; M=-41,146,-58,-45,-51,-56,-59,-58,-55,-49,-49,-28,-70,-62,-62,-43,-28,-46,-80,-61; /M: SY='P'; M=-14,-53,-10, 28,-56,-35,-38,-28, 16,-45, -6, 40, 49, 11,-16, 17, 27,-36,-61,-49; /M: SY='P'; M= 24,-55,-13, -5,-41,-44,-38,-13, 14,-13,-38,-15, 46, 29,-14, 16,-35,-28, 1, 39; /M: SY='P'; M= 6,-13, 4,-15,-51, 16, 20,-16, -4,-14,-41, 1, 46,-10, 11, 22,-18,-23,-59,-27; /I: I=-14; MD=-45; /M: SY='Y'; M=-14,-73,-71,-69,-36,-34,-60, 0,-32, -1,-49,-23,-76,-62,-26,-12,-36,-19,-62, 39; D=-14; /I: I=-14; MI=0; MD=-45; IM=0; DM=-45; /M: SY='C'; M=-25, 65,-24, -1,-26, -9, 16,-50, 4,-47, -8, 12,-19, 40, 23,-12,-31,-40,-43, 60; /M: SY='C'; M=-14,141,-58,-41,-29,-54,-58,-37,-54,-48,-47,-47, -4,-33,-60,-42,-40,-44,-75,-58; /M: SY='W'; M= 22,-58,-16, 16,-31,-39, -1,-23, 4,-18, -1, 11,-18, 9, -6,-18,-26,-46,114, -8; /M: SY='D'; M=-11,-56, 57, 29,-52,-13,-24,-52, 9,-28, 2, -2,-47, -1, 29, 7,-19,-35, 39,-20; /M: SY='H'; M=-39,-57,-14,-31, 13,-53, 59,-39, 29, 15,-32,-28,-54,-10, 30, -9,-42,-18, 58, 43; /M: SY='F'; M= 19,-51,-54,-49, 75,-33,-42, 9, -6, -9,-31,-47,-56,-27, -4, -1,-39,-14,-32, 40; /I: I=-24; MD=-77; /M: SY='G'; M= 18,-52,-31,-41,-58, 61, 16,-59, 15,-58,-14, 37,-48,-17, 0, 6,-34,-54,-58,-50; D=-24; /I: I=-24; MI=-77; IM=-77; DM=-77; /M: SY='N'; M=-45,-53, 85,-21,-62,-37,-27,-61,-31,-64,-56, 86,-49,-32,-40,-29,-31,-60,-79,-51; /I: I=-24; MD=-77; /M: SY='G'; M=-30,-57,-28,-48,-60, 83,-16,-66, 14,-50,-52,-17,-48,-26,-34, -4,-24,-60,-55,-32; D=-24; /I: I=-24; MI=-77; IM=-77; DM=-77; /M: SY='H'; M=-21,-55,-46,-24, 23,-54, 50, 22, -3,-28,-10, -6,-53, 35, 24,-18,-32, 25, -6, 27; /M: SY='C'; M=-41,147,-61,-61,-51,-56,-61,-58,-57,-49,-49,-47,-72,-64,-63,-44,-41,-46,-81,-62; /M: SY='D'; M=-46,-58,101, -3,-65,-41, 4,-64,-33,-63,-59, 48,-47,-32,-41,-23,-35,-62,-81,-49; /M: SY='Q'; M=-12,-58,-13, 39,-52,-35,-36,-35, 28,-19,-27,-10, 47, 47, 3, 0,-24,-36,-54, -1; /I: I=-22; MI=0; MD=-71; IM=0; DM=-71; /M: SY='E'; M= 24,-54, 15, 53,-22, 27, -5,-55,-29,-31,-21, -3,-44, 43,-30, -7,-38,-49,-57,-46; /M: SY='C'; M=-41,147,-61,-61,-51,-56,-61,-58,-57,-49,-49,-47,-72,-64,-63,-44,-41,-46,-81,-62; /M: SY='N'; M=-37,-48, 25,-33,-10,-33,-15,-54,-16,-59,-28,103,-52,-15,-36, 8,-27,-55,-69,-33; /M: SY='N'; M=-30,-46,-27,-40,-10,-18,-33,-27,-35,-22,-41, 85,-49,-35,-41, 26, 42,-12,-63,-14; /M: SY='H'; M= 33,-53,-14, 44,-29,-45, 44,-13,-15,-14,-27,-25, 35,-32,-40, -2,-27,-14,-54, 12; /M: SY='E'; M= 40,-52, 10, 61,-60, 32,-40,-57, -9,-46,-49, -5,-29,-21,-39,-10,-37,-49,-58,-52; /M: SY='C'; M=-40,146,-60,-61,-50,-29,-60,-58,-56,-49,-49,-46,-71,-63,-63,-43,-41,-46,-78,-38; /M: SY='G'; M=-40,-54, 20, 2,-18, 41, -6,-40, -8, 36,-32, 30,-52, 15,-15,-31,-41,-43,-56,-42; /M: SY='W'; M=-54,-62,-66,-59, 80,-58,-26,-38,-52,-32,-37,-41,-62,-54,-39,-54,-53,-45,129, 63; /M: SY='D'; M=-47,-61,111,-11,-68,-44,-33,-66,-34,-64,-63,-15,-47,-34,-43,-35,-37,-63,-83,-50; /M: SY='G'; M=-13,-54,-13,-49,-61, 86,-45,-65,-21,-63,-53, 33,-48,-42,-32,-19,-43,-49,-56,-55; /M: SY='G'; M=-31,-54,-49,-54, 44, 68, -2,-43,-36, 12, 17,-15,-53,-47,-22,-31,-38,-44,-44, -5; /M: SY='D'; M=-47,-61,107, 24,-67,-45,-33,-66,-33,-63,-62,-16,-45,-31,-42,-35,-37,-62,-80,-50; /M: SY='C'; M=-41,147,-61,-61,-51,-56,-61,-58,-57,-49,-49,-47,-72,-64,-63,-44,-41,-46,-81,-62; /I: E1=0; IE=-255; DE=-255; /M: SY='Q'; M= 6,-51, 1, 23,-54,-23,-21,-34, 4,-35,-18, -1,-30, 54,-14, 49, 4,-39,-57,-18; /M: SY='N'; M=-20,-52, -9, 5,-26, 22,-39,-31, 16, 22,-36, 35, -1, 2, 2, 13, -7,-42,-57,-44; /M: SY='N'; M=-19,-12, 24, 15,-54, 25, 24,-43, 17,-47,-35, 51, 0, -8,-36, 2, 0,-22,-62,-19; /M: SY='S'; M=-28,-11,-25, 3, 6,-16, -4, -3, -9, 1, -1, -4, 4, 13,-17, 21, 20, 18, 10,-16; /M: SY='P'; M=-12,-56, 1, 11, -1, 20,-12,-34, 8,-51, -8, 30, 47, 17, -1, -1,-16,-25,-55,-20; /I: I=-19; E1=0; MD=-61; /M: SY='D'; M= 0, 15, 42, 16,-47,-34, 14,-42,-31,-54,-19,-11, 18, 19, -4,-16, 5,-12,-67,-14; D=-19; /I: I=-19; E1=0; MI=0; MD=-61; IM=0; DM=-61; /M: SY='C'; M=-32, 88,-34,-16, -4,-29,-46,-24, 2,-20,-10,-13, 66,-11, 2, 1,-15,-34,-60,-48; /I: E1=0; IE=-255; DE=-255; /M: SY='W'; M=-16,-32,-11,-11,-38,-33,-44, 1, 6, -6,-40, 44, 19,-29, -8, -5, -9,-36,109, -7; /M: SY='P'; M= 25, 21,-26, -8,-17,-23,-42,-16, 23, -7,-26,-42, 38, -4,-16,-10,-22, -4, 19, 33; /M: SY='N'; M=-17, 28, 20, 3,-44, 6, 2, -9, 16,-12,-40, 57,-27,-19, -9,-22,-30,-24, 6, 17; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
Total number of hits | 60 in 21 different sequences |
Number of true positive hits | 60 in 21 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 0 |
Number of false negative sequences | 0 |
Number of 'partial' sequences | 0 |
Precision (true positives / (true positives + false positives)) | 100.00 % |
Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
Matrix type [info] | protein_domain |
Scaling database [info] | window20 |
Author [info] | V_Lesaux |
Taxonomic range [info] | Eukaryotes |
Maximum number of repetitions [info] | 3 |
Feature key [info] | REPEAT |
Feature description [info] | LNR |
Version [info] | 3 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
21 sequences
GLP1_CAEEL (P13508), GNPTA_DANRE (Q5RGJ8), GNPTA_HUMAN (Q3T906), GNPTA_MOUSE (Q69ZN6), LIN12_CAEEL (P14585), NOTC1_CRIGR (G3I6Z6), NOTC1_DANRE (P46530), NOTC1_HUMAN (P46531), NOTC1_MOUSE (Q01705), NOTC1_RAT (Q07008), NOTC1_XENLA (P21783), NOTC1_XENTR (A2RUV0), NOTC2_HUMAN (Q04721), NOTC2_MOUSE (O35516), NOTC2_RAT (Q9QW30), NOTC3_HUMAN (Q9UM47), NOTC3_MOUSE (Q61982), NOTC3_RAT (Q9R172), NOTC4_HUMAN (Q99466), NOTC4_MOUSE (P31695), NOTCH_DROME (P07207)» more
|
PDB [Detailed view] |
12 PDB
1PB5; 2OO4; 3ETO; 3I08; 3L95; 4ZLP; 5CZV; 5CZX; 6XSW; 7ABV; 7S05; 7S06 |