PROSITE documentation PDOC01023Ribosome-binding factor A signature
Ribosome-binding factor A [1] (gene rbfA) is a bacterial protein that associates with free 30S ribosomal subunits. It does not associates with 30S subunits that are part of 70S ribosomes or polysomes. It is essential for efficient processing of 16S rRNA.
Ribosome-binding factor A is a protein of from 13 to 15 Kd which is found in most prokaryotic organisms. A putative chloroplastic form seems to exist in plants [2].
As a signature pattern, we selected the best conserved region which is located in the second half of the protein.
Last update:December 2004 / Pattern and text revised.
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PROSITE method (with tools and information) covered by this documentation:
| 1 | Authors | Bylund G.O. Wipemo L.C. Lundberg L.A. Wikstrom P.M. |
| Title | RimM and RbfA are essential for efficient processing of 16S rRNA in Escherichia coli. | |
| Source | J. Bacteriol. 180:73-82(1998). | |
| PubMed ID | 9422595 |
| 2 | Authors | Bairoch A. |
| Source | Unpublished observations (1998). |
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