PROSITE documentation PDOC00724Ribosomal protein L1e signature
Description
A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists [1,2,3,4] of:
- Vertebrate L1 (L4).
- Drosophila L1.
- Plant L1.
- Yeast L2 (Rp2).
- Fission yeast L2.
- Halobacterium marismortui HmaL4 (HL6).
- Methanococcus jannaschii MJ0177.
These proteins have 246 (archaebacteria) to 427 (human) amino acids. As a signature pattern, we selected a conserved region in the N-terminal part of these proteins.
Last update:December 2004 / Pattern and text revised.
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Technical section
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References
| 1 | Authors | Rafti F. Gargiulo G. Manzi A. Malva C. Graziani F. |
| Title | Sequence of the ribosomal protein cDNA of D. melanogaster homologous to the L1 ribosomal protein gene of X. laevis. | |
| Source | Nucleic Acids Res. 17:456-456(1989). | |
| PubMed ID | 2492096 |
| 2 | Authors | Presutti C. Villa T. Bozzoni I. |
| Title | The primary sequence of the Schizosaccharomyces pombe protein homologous to S.cerevisiae ribosomal protein L2. | |
| Source | Nucleic Acids Res. 21:3900-3900(1993). | |
| PubMed ID | 8367312 |
| 3 | Authors | Bagni C. Mariottini P. Annesi F. Amaldi F. |
| Title | Human ribosomal protein L4: cloning and sequencing of the cDNA and primary structure of the protein. | |
| Source | Biochim. Biophys. Acta 1216:475-478(1993). | |
| PubMed ID | 8268230 |
| 4 | Authors | Arndt E. Kroemer W. Hatakeyama T. |
| Title | Organization and nucleotide sequence of a gene cluster coding for eight ribosomal proteins in the archaebacterium Halobacterium marismortui. | |
| Source | J. Biol. Chem. 265:3034-3039(1990). | |
| PubMed ID | 2406244 |
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