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ENZYME

ENZYME entry: EC 3.4.21.5

Accepted Name
thrombin
Alternative Name(s)
fibrinogenase
Reaction catalysed
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B
Comment(s)
  • More selective than trypsin and plasmin.
  • Belongs to peptidase family S1.
  • Formerly EC 3.4.4.13.
Cross-references
BRENDA3.4.21.5
EC2PDB3.4.21.5
ExplorEnz3.4.21.5
PRIAM enzyme-specific profiles3.4.21.5
KEGG Ligand Database for Enzyme Nomenclature3.4.21.5
IUBMB Enzyme Nomenclature3.4.21.5
IntEnz3.4.21.5
MEDLINEFind literature relating to 3.4.21.5
MetaCyc3.4.21.5
Rhea expert-curated reactions3.4.21.5
UniProtKB/Swiss-Prot
P00735, THRB_BOVINP00734, THRB_HUMANP19221, THRB_MOUSE
Q19AZ8, THRB_PIGQ5R537, THRB_PONABP18292, THRB_RAT
P84122, THRB_SALSA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-