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ENZYME

ENZYME entry: EC 3.1.11.1

Accepted Name
exodeoxyribonuclease I
Alternative Name(s)
E.coli exonuclease I
exonuclease I
Reaction catalysed
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Comment(s)
  • Preference for single-stranded DNA.
  • The Escherichia coli enzyme hydrolyzes glucosylated DNA.
  • Similar enzymes; mammalian DNase III, exonuclease IV, T2- and T4-induced exodeoxyribonucleases.
  • Formerly EC 3.1.4.25.
Cross-references
BRENDA3.1.11.1
EC2PDB3.1.11.1
ExplorEnz3.1.11.1
PRIAM enzyme-specific profiles3.1.11.1
KEGG Ligand Database for Enzyme Nomenclature3.1.11.1
IUBMB Enzyme Nomenclature3.1.11.1
IntEnz3.1.11.1
MEDLINEFind literature relating to 3.1.11.1
MetaCyc3.1.11.1
Rhea expert-curated reactions3.1.11.1
UniProtKB/Swiss-Prot
O28552, DP2L_ARCFUA0RYM0, DP2L_CENSYQ5UZ40, DP2L_HALMA
Q9HMX8, DP2L_HALSAQ18ER3, DP2L_HALWDQ8THG5, DP2L_METAC
Q0W5U6, DP2L_METARQ46E19, DP2L_METBFQ12TF2, DP2L_METBU
Q2FSF9, DP2L_METHJQ59024, DP2L_METJAQ8TUV3, DP2L_METKA
A2SU54, DP2L_METLZA4G0G9, DP2L_METM5A9A8R5, DP2L_METM6
A6VI14, DP2L_METM7Q8PXH2, DP2L_METMAA3CXE7, DP2L_METMJ
Q6M191, DP2L_METMPQ2NHG2, DP2L_METSTO27579, DP2L_METTH
A0B8K5, DP2L_METTPA6URH2, DP2L_METVSQ74N29, DP2L_NANEQ
Q3IU54, DP2L_NATPDQ6L1K9, DP2L_PICTOQ9V2F4, DP2L_PYRAB
P81409, DP2L_PYRFUO57861, DP2L_PYRHOQ9HM33, DP2L_THEAC
Q5JET0, DP2L_THEKOQ97CR6, DP2L_THEVOO28484, DP2S_ARCFU
B0R7U1, DP2S_HALS3Q9HMR7, DP2S_HALSAQ58113, DP2S_METJA
O27456, DP2S_METTHQ9V2F3, DP2S_PYRABP81412, DP2S_PYRFU
O57863, DP2S_PYRHOQ9HLK5, DP2S_THEACP57620, EX1_BUCAI
Q8K923, EX1_BUCAPQ89A43, EX1_BUCBPP04995, EX1_ECOLI
P45188, EX1_HAEINQ9NVH0, EXD2_HUMANQ8VEG4, EXD2_MOUSE
P04536, EXOD_BPT4P94544, POLX_BACSU

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.11.-
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