Expasy logo

ENZYME

ENZYME entry: EC 1.1.99.30

Accepted Name
2-oxo-acid reductase
Alternative Name(s)
(2R)-hydroxycarboxylate-viologen-oxidoreductase
2-oxoacid reductase
HVOR
Reaction catalysed
A + a (2R)-2-hydroxycarboxylate <=> a 2-oxocarboxylate + AH2
Comment(s)
  • Has broad substrate specificity, with 2-oxo-monocarboxylates and 2-oxo-dicarboxylates acting as substrates.
  • Branching in a substrate at the C-3 position results in loss of activity.
  • The enzyme from Proteus sp. is inactivated by oxygen.
Cross-references
BRENDA1.1.99.30
EC2PDB1.1.99.30
ExplorEnz1.1.99.30
PRIAM enzyme-specific profiles1.1.99.30
KEGG Ligand Database for Enzyme Nomenclature1.1.99.30
IUBMB Enzyme Nomenclature1.1.99.30
IntEnz1.1.99.30
MEDLINEFind literature relating to 1.1.99.30
MetaCyc1.1.99.30
Rhea expert-curated reactions1.1.99.30
UniProtKB/Swiss-Prot
Q9R4Y1, HVOR_PROVU

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-