This database was originally developed by the Glaxo (now GSK) group at SIB.
It is no longer maintained and has not been updated since 1996.
However, the information provided by CD40Lbase continues to be valid.
A much more up-to-date database is available.
Pairwise degrees of sequence identity among several TNF family members:
Mo Rat Hu Mo Hu Mo Hu Rat Mo Hu Mo Hu Hu Mo Mo
FasL FasL CD27L CD30L CD30L CD40L CD40L TNFa TNFa TNFa TNFb TNFb Lytb Lytb 4-1BB
Mo FasL 100 93.0 21.2 17.3 19.5 22.6 21.9 31.7 30.3 30.0 34.5 31.0 26.0 25.4 14.7
Rat FasL 100 21.2 18.0 19.5 22.6 21.9 31.7 30.3 31.7 34.5 31.0 26.8 24.6 15.3
Hu CD27L 100 13.5 14.3 17.2 20.1 23.1 24.2 21.8 21.2 21.9 20.3 19.6 14.9
Mo CD30L 100 76.9 14.2 14.2 15.6 15.0 17.7 13.4 14.2 14.2 12.9 16.3
Hu CD30L 100 16.4 14.2 17.7 17.1 19.9 16.4 14.2 14.9 13.7 16.3
Mo CD40L 100 74.7 26.1 25.4 27.3 22.3 21.6 22.4 23.1 16.3
Hu CD40L 100 23.9 23.9 25.9 22.3 23.0 21.0 21.0 16.3
Rat TNFa 100 94.7 78.1 39.6 36.8 24.5 23.0 14.1
Mo TNFa 100 78.8 41.0 37.5 26.0 23.0 13.5
Hu TNFa 100 38.6 34.5 26.5 23.5 13.4
Mo TNFb 100 78.5 26.8 36.4 14.8
Hu TNFb 100 27.5 27.0 15.5
Hu Lytb 100 78.6 13.6
Mo Lytb 100 11.9
Mo 4-1BBL 100
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